Prof. Jack Henion
Cornell University
College of Veterinary Medicine
Advion Biosciences Inc
Ithaca, New York
USA

“Quality of Life, an integrated future of Medicine and Nutrition research: challenges for LC/MS technology”.

Prof. Dr. Jan van der Greef
TNO Quality of Life and the LACDR at Leiden University
The Netherlands

"Aerosol-Cloud-Climate Interactions: Possibilities and Limits of Off-line and On-line Mass Spectrometric Techniques"

“LC-MS and Multivariate Analysis: a happy marriage?”.

Prof.Age Smilde
TNO Quality of Life and Swammerdam Institute for Life Sciences
University of Amsterdam
The Netherlands

“Improving the Analytical Strategies for Metabolomics”

Prof. Thomas Hankemeier
LACDR and Netherlands Metabolomics Centre
Leiden University
The Netherlands

“A revolution in tailor-made LC for LC/MS: POPLC?”

Prof. Karl-Siegfried Boos
Laboratory of BioSeparation Institute of Clinical Chemistry
Medical Center of the University of Munich
Germany

Final Program ( PDF )

Vendors Highlight Sessions

Wednesday, November 12, 2008

09.00

Opening Jan van der Greef

09.05

”Roland W. Frei Lecture”
Ruedi Aebersold, ETH Zurich, Institute of Molecular Systems Biology, Zurich, CH
LC-MS/MS Methods for the Discovery and Measurement of the Proteome

09.45

“Silver Edition Lecture”
Jack Henion, Advion BioSciences, Inc, Ithaca, USA
A Historical Perspective of the Montreux LC/MS Symposium: Then, Now and the Future

10.25

Coffee break

10.55

Neil Spooner, GlaxoSmithKline, Ware,UK
The Use of Dried Blood Spot Samples for Quantitative Bioanalysis of Drugs in PreClinical and Clinical Studies

11.10

Pier Luigi Mauri, Institute for Biomedical Technologies, Segrate (Milan), IT
Protein profiles of Formalin-Fixed Paraffin-Embedded (PFFE) Samples from Gastric Cancer using MudPIT Proteomic Approach

11.25

Michel Nielen, Wageningen UR/RIKILT-Institute of Food Safety, Wageningen, NL
DESI Mass Spectrometry Analysis on a Surface Plasmon Resonance Bioaffinity Chip

11.40

Wayne P. Duncan, Agilent Technologies, Inc, Santa Clara, CA, USA
High Throughput Drug Discovery Analysis Using LC/MS/Multimode source/ELSD/CLND with Enhanced Data Review Capabilities

11.55

Leon Coulier, TNO Quality of Life, Zeist , NL
New Analytical Approaches in Food Analysis: Reaction of Food Contaminants and Ingredients using LC-MS

12.10

Carola Damen, Slotervaart Hospital / the Netherlands Cancer Institute, Amsterdam, NL
The Use of Electrospray Ionization Quadrupole Ion-Mobility Time-of-Flight Mass Spectrometry as a Tool for the Structural elucidation of the Therapeutic Monoclonal Antibody Trastuzumab (Herceptin®)

12.25

Lunch break

14.00

Poster presentations

16.00

Keynote lecture
Thorsten Hoffmann, Johannes Gutenberg-Universität Mainz, Mainz, DE
Aerosol-Cloud-Climate Interactions: Possibilities and Limits of Off-line and On-line Mass Spectrometric Techniques

16.35

Rosa Morello, Laboratory of BioSeparation, Institute of Clinical Chemistry, Medical Center of the University of Munich, Munich, DE
Automated Processing of Whole Blood for LC-MS analysis

16.50

Reza Javahery, IONICS Mass Spectrometry Group, Bolton, USA
Go with the Flow: Transporting Ions using Gas Flow in Atmospheric Pressure Ionization Mass Spectrometry

17.05

Günter Allmaier, University of Vienna, Vienna, A
Nano ES/Charge Reduction Attached to an Ion Mobility Spectrometer and a Parallel Ion Mobility Spectrometer: a Technique for the Analysis and Micropreparative Collection of Nanobioparticles

17.20

Lester Taylor, Thermofisher, Bremen, DE
Applications of the High Resolution Exactive Benchtop Orbitrap Mass Spectrometer for Compound Screening and Quantification

17.35-19.00

Symposium Welcome Reception

Thursday, November 13, 2008

Metabolomics Session

09.00

Keynote lecture
09.00 Thomas Hankemeier, Leiden University/NMC, Leiden, NL
Improving the Analytical Strategies for Metabolomics

09.35

Theresa Koal, Biocrates Life Sciences AG, Insbruck, A
Targeted Metabolomics - Quantitative LC/MS/MS Analysis of Energy Metabolism and Eicosanoid Intermediates and Cholesterol Derivatives in Low Volume Biological Samples

09.50

Jurre Kamphorst, Leiden University, Leiden, NL
Novel strategies in Peptidomics for Osteoarthritis Biomarker Discovery

10.05

Emma Marsden-Edwards, Waters Corporation, Manchester, UK
A Metabolomic LC/MS Approach for the Analysis of Japanese Green Tea using Integrated Statistical Data Handling/Processing to Mine Complex Samples

10.20

Coffee break

10.50

Key note lecture
Ina Schuppe-Koistinen, Astrazeneca.R&D, Södertälje, SE
Endogenous Metabolite Profiling in Drug R&D: Opportunities for Biomarker Discovery and Personalized Healthcare

11.25

Keynote lecture
Age Smilde, UvA, Swammerdam Institute for Life Sciences, Amsterdam, NL
LC-MS and Multivariate Analysis: A Happy Marriage?

12.00

George McLeod, Bruker Daltonik GmbH, Bremen, DE
Pushing the Limit: a Novel Mass Spectrometer combining Ultra-high Mass Resolution and Accuracy with Fast Data Acquisition Speed

12.15

Peter Hoffmann, University of Leipzig, Institute of Analytical Chemistry, Leipzig, DE
Microfluidic Glass Chips with Integrated Nanoelectrospray Emitters for ultra high speed CE-MS coupling

12.30

Lunch break

14.00

Poster presentations

16.00

Keynote lecture
Jan Van der Greef, TNO, Quality of Life, Zeist , NL
Quality of Life, an Integrated Future of Medicine and Nutrition Research: Challenges for LC/MS Technology

Vendors Session

16.35

Dragan Vuckovic, IONICS Mass Spectrometry Group, Bolton, USA
Presenting Ionics 3Q Molecular Analyzer: A new flow-based triple quadrupole mass spectrometer

16.45

Lester Taylor, Thermofisher, Bremen, DE
Exactive:Development of a new high resolution benchtop Orbitrap mass spectrometer

16.55

Robert Plumb, Waters corp, Milford, USA
A Simple Strategy For High Throughput Bioanalysis Using Sub 2um Particle LC/MS/MS

17.05

Rebecca E. Wittrig, Restek Corporation, Bellefonte, PA, USA
Using Both Small Particle Size HPLC Packings and Unique Stationary Phases for Improved Resolution in Challenging Separations

17.15

Dave Bell, Supelco /Sigma-Aldrich, Bellefonte, PA, USA
Aqueous-Normal Phase/HILIC in LC-MS Separations: Retention Mechanisms and Their Impact on Retention and Selectivity

17.25

Ralf Bogumil, Biocrates Life Sciences AG, Insbruck, A
Targeted Metabolomics - Robust Analysis of Human Plasma using Automated Sample Preparation and fast FIA-MS/MS Detection

19.30-22.30

Conference dinner at Fairmont, Le Montreux Palace,
Le Petit Palais.

Friday, November 14, 2008

09.00

Horst Schroeder, Institute of Environmental Engineering, Environmental Analytical Laboratory, RWTH Aachen University, Aachen, DE
Occurence and Follow-Up of Anabolic and Doping Drugs During Municipal Wastewater Treatment Applying High Resolution Liquid Chromatography-Mass Spectrometry (LC-MS and -MSn)

09.15

Reinaldo Almeida, Advion BioSciences, Norwich, UK
A novel chromatographic method allows online reanalysis with a single injection

9.30

Niklas Lindegardh, Mahidol-Oxford Tropical Medicine Research Unit, Bangkok, TH
Sensitive assays using HILIC-SPE or HILIC-LC-MS/MS for quantification of hydrophilic anti-influenza drugs

09.45

Keynote lecture
Karl-Siegfried Boos, Laboratory of BioSeparation, Institute of Clinical Chemistry, Medical Center of the University of Munich, DE
and
Stefan Lamotte, Bischoff Analysentechnik, Leonberg, DE
A revolution in tailor-made LC for LC-MS: POPLC?

10.20

Coffee break

10.50

Vladimir Havlicek, Institute of Microbiology, Prague, CZ
DESI-FTICR: Principles and Applications

11.05

Erdmann Rapp, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, DE
Atmospheric pressure free liquid infrared matrix assisted laser dispersion ionisation: Unifying LC-MS interfaces

11.20

Olivier Heudi, Novartis Pharma AG, DMPK/Bioanalytics, Basel, CH
Towards absolute quantification of therapeutic monoclonal antibody in serum by LC-MS/MS using isotope-labeled antibody standard and protein cleavage isotope dilution mass spectrometry

11.35

Michael J. Taylor, Sasa Scottish Government, Edinburgh, UK
The application of UPLC Time-of-Flight Mass Spectrometry for the Quantitative & Qualitative Determination of Target Analytes present in Complex Mixtures

11.50

Anneke Muehlebach, Solvay Pharmaceuticals Research Laboratories, Hannover, DE
Sacrificing Quality for Throughput? Fast Serial UPLC-UV-ELS-MS Analysis in Drug Discoverys

12.05

RJennifer Townsend, LCMS Limited, Raleigh, USA
Novel aspects of Quatitation of Immonogenic Gluten peptides by
LC/MS/MS

12.20

Presentation next meeting by Jack Henion

12.25

“Roland W. Frei”- poster award presentd by Dieter Klockow

12.35 - 12.40

Closure of the meeting

Scientifc program: PDF